Intensive Care Management of Multiorgan Dysfunction and Hypoxic Brain Injury Secondary to Refractory Status Epilepticus

Sanum Kashif


Refractory Status Epilepticus (RSE) is a medical emergency that may lead to permanent brain damage or death. Mortality rate is 16-39%. It is the life threatening condition in which continuous fits occur, despite treatment with benzodiazepines and one antiepileptic drug.
A 25-year-old female, brought in emergency department with high-grade fever and frequent fits. Glasgow Coma Scale (GCS) was 3/15 with unstable hemodynamics. Resuscitation started immediately and managed as status epilepticus. Patient was in multi organ failure on arrival. On the basis of history and examination, hypoxic brain injury was diagnosed initially. Later on, refractory status epilepticus (RSE) with multi organ dysfunction syndrome (MODS) was  diagnosed, after necessary investigations and treatment. Patient was managed as a team with multidisciplinary approach and after continuous effort of 2 weeks, patient was successfully discharged to home.

Key Words:  Intensive Care, Mutiorgan Dysfunction Syndrome (MODS), Refractory Status Epilepticus (RSE).

How to cite this: Kashif S. Intensive Care Management of Multiorgan dysfunction and Hypoxic brain injury secondary to   refractory status epilepticus. Life and Science. 2021; 2(4): 198-200.  doi:

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